FILE - House Speaker Nancy Pelosi of California holds the gavel at the Capitol in Washington, Jan. 3, 2019. (AP Photo/Carolyn Kaster, File)

WASHINGTON (AP) — Speaker Emerita Nancy Pelosi will not seek reelection to the U.S. House, bringing to a close her storied career as not only the first woman in the speaker’s office but arguably the most powerful in American politics.

Pelosi, who has represented San Francisco for nearly 40 years, announced her decision Thursday.

“I will not be seeking reelection to Congress,” Pelosi said in a video address to voters.

Pelosi, appearing upbeat and forward-looking as images of her decades of accomplishments filled the frames, said she would finish out her final year in office. And she left those who sent her to Congress with a call to action to carry on the legacy of agenda-setting both in the U.S. and around the world.

“My message to the city I love is this: San Francisco, know your power,” she said. “We have made history. We have made progress. We have always led the way.”

Pelosi said, “And now we must continue to do so by remaining full participants in our democracy and fighting for the American ideals we hold dear.”

The decision, while not fully unexpected, ricocheted across Washington, and California, as a seasoned generation of political leaders is stepping aside ahead of next year’s midterm elections. Some are leaving reluctantly, others with resolve, but many are facing challenges from newcomers eager to lead the Democratic Party and confront President Donald Trump.

Pelosi, 85, remains a political powerhouse and played a pivotal role with California’s redistricting effort, Prop 50, and the party’s comeback in this week’s election. She maintains a robust schedule of public events and party fundraising, and her announced departure touches off a succession battle back home and leaves open questions about who will fill her behind-the-scenes leadership role at the Capitol.

Former President Barack Obama said Pelosi will go down in history as “one of the best speakers the House of Representatives has ever had.”

An architect of the Affordable Care Act during Obama’s tenure, and a leader on the international stage, Pelosi came to Congress later in life, a mother of five mostly grown children, but also raised in a political family in Baltimore, where her father and brother both served in elected office.

Long criticized by Republicans, who have spent millions of dollars on campaign ads vilifying her as a coastal elite and more, Pelosi remained unrivaled. She routinely fended off calls to step aside by turning questions about her intentions into spirited rebuttals, asking if the same was being posed of her seasoned male colleagues on Capitol Hill.

In her video address, she noted that her first campaign slogan was “a voice that will be heard.”

And with that backing, she became a speaker “whose voice would certainly be heard,” she said.

But after Pelosi quietly helped orchestrate Joe Biden’s withdrawal from the 2024 presidential race, she has decided to pass the torch, too.

Last year, she experienced a fall resulting in a hip fracture during a whirlwind congressional visit to allies in Europe, but even still it showcased her grit: It was revealed she was rushed to a military hospital for surgery — after the group photo, in which she’s seen smiling, poised on her trademark stiletto heels.

Pelosi’s decision also comes as her husband of more than six decades, Paul Pelosi, was gravely injured three years ago when an intruder demanding to know “Where is Nancy?” broke into the couple’s home and beat him over the head with a hammer. His recovery from the attack, days before the 2022 midterm elections, is ongoing.

Ahead of the 2026 midterm elections, Pelosi faced a potential primary challenge in California. Newcomer Saikat Chakrabarti, who helped devise progressive Rep. Alexandria Ocasio-Cortez’s political rise in New York, has mounted a campaign, as has state Sen. Scott Wiener.

While Pelosi remains an unmatched force for the Democratic Party, having fundraised more than $1 billion over her career, her next steps are uncertain.

First elected in 1987 after having worked in California state party politics, she has spent some four decades in public office.