TORONTO — Jose Ramirez homered to cap a three-run 10th inning and the Cleveland Indians beat the Blue Jays 5-2 Monday, snapping Toronto’s four-game winning streak.

Vladimir Guerrero Jr. hit his 34th home run for the Blue Jays, who lost for the first time in four games since returning north of the border to Rogers Centre.

Recently acquired Toronto reliever Brad Hand (5-6) endured a rocky 10th, opening the inning with a wild pitch that allowed automatic runner Myles Straw to advance to third. Amed Rosario lined Hand’s next pitch through the drawn-in infield for an RBI single.

Four pitches later, Ramirez homered off the left field foul screen, his 23rd.

“I was looking for a high pitch and thankfully that happened,” Ramirez said through a translator. “He threw that high pitch and I was able to put the ball in play.”

It was the 150th homer of Ramirez’s career, 11 of which have come in the ninth inning or later.

Bryan Shaw (4-5) worked one inning for the win and Emmanuel Clase finished for his 14th save in 18 opportunities.

Cleveland is 6-5 in extra innings while Toronto is 2-6.

Harold Ramirez and Oscar Mercado had back-to-back RBI singles off Blue Jays left-hander Robbie Ray in third. Toronto tied it on Guerrero’s two-run homer off rookie right-hander Eli Morgan in the sixth.

Recalled from Triple-A Columbus before the game, Morgan allowed two runs and five hits in career-high six innings. He walked one and matched a career-high by striking out nine.

Jose Ramirez said Morgan did a “tremendous job,” and acting manager DeMarlo Hale called Morgan’s performance “outstanding.”

“I thought he was one step ahead of them the first two times around the order because he threw his fastball a lot more,” Hale said.

Ray gave up two runs and six hits in six innings.

“They definitely made me work today,” Ray said.

CATCH OF THE DAY

Straw made a sliding catch on George Springer’s drive to right-center to begin the ninth.

“I thought I had a good chance off the bat and sure enough I was able to get to it,” Straw said.

ROSTER MOVES

The Indians activated 1B Bobby Bradley off the bereavement list and optioned OF Daniel Johnson and INF Yu Chang to Triple-A. Both Johnson and Chang will remain on the taxi squad.