LOS ANGELES (AP) — Wallis Annenberg, the billionaire philanthropist who supported the arts, science, education and animal welfare causes over decades in Los Angeles, died Monday, her family said.

She was 86.

Annenberg died at home from complications related to lung cancer, the family said in a statement to the Los Angeles Times.

“Wallis transitioned peacefully and comfortable this morning to her new adventure,” the statement said. “Cancer may have beaten her body but it never got her spirit. We will hold her and her wisdom in our hearts forever.”

Her name adorns institutions across the Los Angeles area, including the Wallis Annenberg Building at the California Science Center, the Wallis Annenberg GenSpace senior center and the Wallis Annenberg Center for the Performing Arts.

The Wallis Annenberg Wildlife Crossing, the world’s largest bridge for animals on the move, will open next year over an LA freeway.

During her 16-year tenure as president and chief executive of the Annenberg Foundation, the nonprofit organization has donated about $1.5 billion to thousands of organizations in Southern California, the Times reported.

Under Wallis Annenberg’s leadership, the foundation expanded its philanthropic scope beyond media, arts and education to include animal welfare, environmental conservation and healthcare.

“Wallis Annenberg blessed the Los Angeles community not only with her philanthropy, but also with her guidance about how to improve our community,” said LACMA Chief Executive Michael Govan, who filled that endowed position in 2006.