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Q. After reading your article on lipoprotein(a), I wanted to share my experience. In February of 2024, I thought I had indigestion. When antacids did not relieve the symptoms, I went to the emergency room and was diagnosed with a mild heart attack.
My weight is normal; I exercise often and have well-controlled blood pressure and slightly elevated cholesterol levels. My primary care doctor did not have me on statins.
A heart catheterization revealed that I had four major blockages in my coronary arteries, and I had a quadruple bypass operation. My doctor said I was the last patient he would have expected to have heart problems. The cardiologist I have seen since my surgery did not test my Lp(a) levels. After seeing a news segment, I requested testing. My level was 345 nmol/L!
Although there is currently no treatment available, I believe testing is important. Because of the possible hereditary link, I urged my children to be tested. Their levels are very low. Fortunately, my heart is not damaged, but I am aware of potential risks. Keep urging your readers to be tested.
A. We are shocked that your cardiologist did not order a test for Lp(a). The American College of Cardiology recently updated its guidelines and now recommends that everyone be tested for this risk factor at least once. Your level was extremely high and might well explain why you had a heart attack and clogged arteries.
A new clinical trial of the drug pelacarsen to lower Lp(a) yielded disappointing results. It worked to reduce Lp(a) but did not prevent heart attacks and strokes.
There are other ways to manage this risk. You can learn more about aspirin, niacin, PCSK9 inhibitors and diet in our "eGuide to Cholesterol Control & Heart Health." This online resource may be found under the Health eGuides tab at www.PeoplesPharmacy.com.
In their column, Joe and Teresa Graedon answer letters from readers. Write to them in care of King Features, 300 W. 57th St., 41st Floor, New York, NY 10019, or email them via their website: www.PeoplesPharmacy.com.