The Eagles led 23-13 late in the fourth quarter, but could not hold on against the Irish.
The Penguins hadn't beaten the Golden Flashes in Kent since 1996.
The Buckeyes trail Alabama, Oregon, Florida State, Mississippi State and TCU.
Hubbard, Ursuline and Western Reserve are the Valley's surviving high school football teams.
Fourteen area teams made the playoffs.
Cole Durina scored the only goal of the match in overtime.
Poland forced overtime in the final minute of regulation.
Beachwood will face South Range in a regional final at noon on Saturday at Ravenna High School.
South Range will play in a regional final at noon on Saturday.
Akron Hoban beat Hubbard, 27-25,25-17 and 25-18.