Tissue Nanotransfection

Tissue Nanotransfection


Researchers at The Ohio State University Wexner Medical Center and Ohio State’s College of Engineering have developed a new technology, Tissue Nanotransfection (TNT), that can generate any cell type of interest for treatment within the patient’s own body.

This technology may be used to repair injured tissue or restore function of aging tissue, including organs, blood vessels and nerve cells. Results of the regenerative medicine study was published in the journal “Nature Nanotechnology.”

“By using our novel nanochip technology, injured or compromised organs can be replaced. We have shown that skin is a fertile land where we can grow the elements of any organ that is declining,” said Dr. Chandan Sen, director of Ohio State’s Center for Regenerative Medicine & Cell Based Therapies, who co-led the study with L. James Lee, professor of chemical and biomolecular engineering with Ohio State’s College of Engineering in collaboration with Ohio State’s Nanoscale Science and Engineering Center.

Researchers studied mice and pigs in these experiments; and were able to reprogram skin cells to become vascular cells in badly injured legs that lacked blood flow. Within one week, active blood vessels appeared in the injured leg, and by the second week, the leg was saved. In lab tests, this technology was also shown to reprogram skin cells in the live body into nerve cells that were injected into brain-injured mice to help them recover from stroke. Researchers plan to start clinical trials next year to test this technology in humans. Diabetes Empowerment Education Program


The Mahoning County District Board of Health is sponsoring a free Diabetes Empowerment Education Program (DEEP) for people with type 1, type 2 and pre-diabetes. DEEP is an interactive small group workshop that takes place once a week for six weeks.

The program encourages small lifestyle changes while learning about diabetes and the way it affects health. Classes offered are: Jan. 3, 2018, and Feb. 7, 2018, at the Jewish Community Center, Gypsy Lane, Youngstown, from 11 a.m. to 1 p.m.; and Jan. 16, 2018, and Feb. 20, 2018 at the Davis Family YMCA, Boardman, from 10 a.m. to noon. YMCA membership not required. Registration is required. For information, call 330-270-2855 ext. 109. SFlbStop the snore

Ellicott City, Md.

There are steps that can be taken to end spouse snoring and perhaps save their lives in the process, says Dr. Gene Sambataro, DDS, author of the book “Stop the Snore: Dental Solutions for Healthy Sleep.”

Snoring is annoying and causes the spouse to lose sleep, but it can also be detrimental to the snorer’s health. When someone snores, it means that their airway is being obstructed while they sleep. It’s important for anyone who snores to get evaluated by a qualified professional; and anyone who knows someone who snores should urge that person to get checked because there’s a good chance they don’t even realize they snore.

Sambataro offers suggestions to end snoring.

Get tested for sleep apnea: The National Sleep Foundation reports that about 18 million American adults suffer from obstructive sleep apnea and that 90 percent are undiagnosed.

Change sleeping positions: Sleeping on your back will increase snoring and worsen your sleep apnea.

Watch your weight: Weight gain can cause a person to develop a thicker neck which contributes to narrowing of the airway.

Practice good sleep hygiene: Poor sleep habits, such as staying up too late, can lead to more snoring.

Get rid of dust: Sometimes people have trouble breathing through their nose because of an allergy causing them to snore. The culprit behind the allergy could be dust.

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