facebooktwitterRSS
- Advertisement -
  • Most Commentedmost commented up
  • Most Emailedmost emailed up
  • Popularmost popular up
- Advertisement -
 

« News Home

Study shows Plavix a risk for returning ulcers



Published: Thu, January 20, 2005 @ 12:00 a.m.



BOSTON (AP) -- Plavix, a heart drug recommended by medical groups as an easy-on-the-stomach substitute for aspirin, instead showed a much higher risk of recurrent ulcers in a small but provocative study.

The study could upend the treatment guidelines for tens of thousands of Americans who must take anti-clotting drugs for their hearts but are prone to gastrointestinal problems.

"These are very surprising findings, because the conventional wisdom is that Plavix is a GI-safe medicine -- or I should say 'has been' a GI-safe medicine," said Dr. Byron Cryer of the University of Texas Southwestern Medical School and Veterans Affairs hospital in Dallas.

He said he has stopped prescribing Plavix to his own patients who have a high risk of ulcers, but believes the drug is still OK for others. He said the U.S. guidelines for Plavix should be re-evaluated in light of the findings.

He wrote an editorial to accompany the study, published in today's New England Journal of Medicine.

The findings, reached by Hong Kong researchers, come as a surprise because Plavix was gentle on the stomach in previous testing. However, the patients in earlier research had a normal ulcer risk overall. This study was the first one to look at patients who had already had an ulcer.

An estimated 50 million Americans take aspirin, the inexpensive old standby, to ward off heart attacks and strokes. But aspirin can cause bleeding, ulcers or other stomach problems in perhaps a third of users.

Copyright 2005 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.




Comments

Use the comment form below to begin a discussion about this content.


News
Opinion
Entertainment
Sports
Marketplace
Classifieds
Records
Discussions
Community
Help
Forms
Neighbors

HomeTerms of UsePrivacy StatementAdvertiseStaff DirectoryHelp
© 2014 Vindy.com. All rights reserved. A service of The Vindicator.
107 Vindicator Square. Youngstown, OH 44503

Phone Main: 330.747.1471 • Interactive Advertising: 330.740.2955 • Classified Advertising: 330.746.6565
Sponsored Links: Vindy Wheels | Vindy Jobs | Vindy Homes | Pittsburgh International Airport